Lion's mane mushroom, scientifically known as Hericium erinaceus, has a rich history deeply rooted in traditional Asian medicine, particularly in China and Japan. Its use dates back centuries, with records of its consumption and medicinal properties found in ancient texts. In traditional Chinese medicine, lion's mane mushroom was highly regarded for its potential health benefits. It was often referred to as "the monkey head mushroom" or "the bearded tooth fungus" due to its distinctive appearance with long, cascading spines resembling a lion's mane. Historical texts from China, such as the "Ben Cao Bei Yao" (Differences between Various Types of Materia Medica), documented its use in traditional herbal remedies, where it was believed to support digestive health, strengthen the immune system, and promote overall vitality.

In Japan, lion's mane mushroom is known as "Yamabushitake," and its use can be traced back to at least the 17th century. It was traditionally consumed for its potential cognitive benefits and believed to enhance mental clarity and focus. In Japanese culture, it has been used both as a culinary delicacy and a medicinal tonic. Over the years, this mushroom's reputation has grown beyond traditional medicine, as modern research has begun to uncover its potential health-promoting properties, particularly its effects on neurological health and cognitive function.

In recent years, lion's mane mushroom has gained popularity in the West as an adaptogen and nootropic, believed to support brain health and cognitive function. It is often used in dietary supplements and functional foods marketed for its potential cognitive benefits.